Key signalling nodes in mammary gland development and cancer. Mitogen-activated protein kinase signalling in experimental models of breast cancer progression and in mammary gland development

Seven classes of mitogen-activated protein kinase (MAPK) intracellular signalling cascades exist, four of which are implicated in breast disease and function in mammary epithelial cells. These are the extracellular regulated kinase (ERK)1/2 pathway, the ERK5 pathway, the p38 pathway and the c-Jun N-...

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Bibliographic Details
Main Authors: Whyte, Jacqueline, Bergin, Orla, Bianchi, Alessandro, McNally, Sara, Martin, Finian
Format: Artigo
Language:Inglês
Published: BioMed Central 2009
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790844/
https://ncbi.nlm.nih.gov/pubmed/19818165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2361
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