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Comparative Dynamics of NMDA- and AMPA-Glutamate Receptor N-Terminal Domains
Ionotropic glutamate receptors (iGluRs) harbor two extracellular domains: the membrane-proximal ligand-binding domain (LBD) and the distal N-terminal domain (NTD). These are involved in signal sensing: the LBD binds L-glutamate, which activates the receptor channel. Ligand binding to the NTD modulat...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cell Press
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3496038/ https://ncbi.nlm.nih.gov/pubmed/22959625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.08.012 |
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