Structural characterization and inhibition of the Plasmodium Atg8-Atg3 interaction

The autophagy-related proteins are thought to serve multiple functions in Plasmodium and are considered essential to parasite survival and development. We have studied two key interacting proteins, Atg8 and Atg3, of the autophagy pathway in P. falciparum. These proteins are vital for the formation a...

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Hlavní autoři: Hain, Adelaide U.P., Weltzer, Ryan R, Hammond, Holly, Jayabalasingham, Bamini, Dinglasan, Rhoel R., Graham, David R. M., Colquhoun, David R., Coppens, Isabelle, Bosch, Jürgen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496014/
https://ncbi.nlm.nih.gov/pubmed/22982544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2012.09.001
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