Structural characterization and inhibition of the Plasmodium Atg8-Atg3 interaction

The autophagy-related proteins are thought to serve multiple functions in Plasmodium and are considered essential to parasite survival and development. We have studied two key interacting proteins, Atg8 and Atg3, of the autophagy pathway in P. falciparum. These proteins are vital for the formation a...

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Detalhes bibliográficos
Main Authors: Hain, Adelaide U.P., Weltzer, Ryan R, Hammond, Holly, Jayabalasingham, Bamini, Dinglasan, Rhoel R., Graham, David R. M., Colquhoun, David R., Coppens, Isabelle, Bosch, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496014/
https://ncbi.nlm.nih.gov/pubmed/22982544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2012.09.001
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