CD40-Induced Signaling in Human Endothelial Cells Results in mTORC2- and Akt-Dependent Expression of Vascular Endothelial Growth Factor In Vitro and In Vivo()

We have examined CD40-dependent signals in endothelial cells (EC) mediating the expression of vascular endothelial growth factor (VEGF) and VEGF-induced angiogenesis. We treated confluent cultures of EC with soluble CD40L (sCD40L), and by Western blot found a marked increase in the phosphorylation o...

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Autores principales: Dormond, Olivier, Contreras, Alan G., Meijer, Esther, Datta, Dipak, Flynn, Evelyn, Pal, Soumitro, Briscoe, David M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495983/
https://ncbi.nlm.nih.gov/pubmed/19018001
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