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Cutting Edge: Vascular Endothelial Growth Factor-Mediated Signaling in Human CD45RO(+) CD4(+) T Cells Promotes Akt and ERK Activation and Costimulates IFN-γ Production
In this study, we find that CD45RO(+) memory populations of CD4(+) T lymphocytes express the vascular endothelial growth factor (VEGF) receptors KDR and Flt-1 at both the mRNA and protein levels. Furthermore, by Western blot analysis, we find that VEGF increases the phosphorylation and activation of...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3495980/ https://ncbi.nlm.nih.gov/pubmed/20008289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900397 |
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