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dj-1β regulates oxidative stress, insulin-like signaling and development in Drosophila melanogaster

DJ-1 (or PARK-7) is a multifunctional protein implicated in numerous pathologies including cancer, sterility and Parkinson disease (PD). The popular genetic model Drosophila melanogaster has two orthologs, dj-1: α and β. Dysfunction of dj-1β strongly impairs fly mobility in an age-dependent manner....

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Библиографические подробности
Главные авторы: Stefanatos, Rhoda, Sriram, Ashwin, Kiviranta, Essi, Mohan, Aravind, Ayala, Victoria, Jacobs, Howard T., Pamplona, Reinald, Sanz, Alberto
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495829/
https://ncbi.nlm.nih.gov/pubmed/22983063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.22073
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