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Recognition of chemical carcinogen-modified DNA by a DNA-binding protein.

Using a filter binding assay, we have detected and partially purified a protein from human placenta that has a high affinity for N-acetoxy-2-acetylaminofluorene-modified double-stranded DNA (AAF-[3H]DNA) of bacteriophage T7. This protein has been partially purified from a 1 M NaCl extract of a crude...

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Detalhes bibliográficos
Main Authors: Moranelli, F, Lieberman, M W
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC349582/
https://ncbi.nlm.nih.gov/pubmed/6932015
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