Recognition of chemical carcinogen-modified DNA by a DNA-binding protein.
Using a filter binding assay, we have detected and partially purified a protein from human placenta that has a high affinity for N-acetoxy-2-acetylaminofluorene-modified double-stranded DNA (AAF-[3H]DNA) of bacteriophage T7. This protein has been partially purified from a 1 M NaCl extract of a crude...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1980
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349582/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6932015/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.6.3201 |
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