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A prototypical Fanconi anemia pathway in lower eukaryotes?

DNA interstrand cross-links (ICLs) present a major challenge to cells, preventing separation of the two strands of duplex DNA and blocking major chromosome transactions, including transcription and replication. Due to the complexity of removing this form of DNA damage, no single DNA repair pathway h...

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Bibliographic Details
Main Authors: McHugh, Peter J., Ward, Thomas A., Chovanec, Miroslav
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495816/
https://ncbi.nlm.nih.gov/pubmed/22895051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.21727
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