Modest Elevation in BNP in Asymptomatic Hypertensive Patients Reflects Sub-Clinical Cardiac Remodeling, Inflammation and Extracellular Matrix Changes

In asymptomatic subjects B-type natriuretic peptide (BNP) is associated with adverse cardiovascular outcomes even at levels well below contemporary thresholds used for the diagnosis of heart failure. The mechanisms behind these observations are unclear. We examined the hypothesis that in an asymptom...

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Detalhes bibliográficos
Main Authors: Phelan, Dermot, Watson, Chris, Martos, Ramon, Collier, Patrick, Patle, Anil, Donnelly, Seamas, Ledwidge, Mark, Baugh, John, McDonald, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495762/
https://ncbi.nlm.nih.gov/pubmed/23152884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049259
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