Modest Elevation in BNP in Asymptomatic Hypertensive Patients Reflects Sub-Clinical Cardiac Remodeling, Inflammation and Extracellular Matrix Changes

In asymptomatic subjects B-type natriuretic peptide (BNP) is associated with adverse cardiovascular outcomes even at levels well below contemporary thresholds used for the diagnosis of heart failure. The mechanisms behind these observations are unclear. We examined the hypothesis that in an asymptom...

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Main Authors: Phelan, Dermot, Watson, Chris, Martos, Ramon, Collier, Patrick, Patle, Anil, Donnelly, Seamas, Ledwidge, Mark, Baugh, John, McDonald, Ken
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
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Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495762/
https://ncbi.nlm.nih.gov/pubmed/23152884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049259
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