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Sequential medical trials

A model for sequential clinical trials is discussed. Three proposed stopping rules are studied by the Monte Carlo method for small patient horizons and mathematically for large patient horizons. They are shown to be about equally effective and asymptotically optimal from both Bayesian and frequentis...

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Detalhes bibliográficos
Main Authors: Lai, T. L., Levin, Bruce, Robbins, Herbert, Siegmund, David
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC349568/
https://ncbi.nlm.nih.gov/pubmed/16592839
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