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Sequential medical trials

A model for sequential clinical trials is discussed. Three proposed stopping rules are studied by the Monte Carlo method for small patient horizons and mathematically for large patient horizons. They are shown to be about equally effective and asymptotically optimal from both Bayesian and frequentis...

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書目詳細資料
Main Authors: Lai, T. L., Levin, Bruce, Robbins, Herbert, Siegmund, David
格式: Artigo
語言:Inglês
出版: 1980
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC349568/
https://ncbi.nlm.nih.gov/pubmed/16592839
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