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A closed-tube methylation-sensitive high resolution melting assay (MS-HRMA) for the semi-quantitative determination of CST6 promoter methylation in clinical samples

BACKGROUND: CST6 promoter is highly methylated in cancer, and its detection can provide important prognostic information in breast cancer patients. The aim of our study was to develop a Methylation-Sensitive High Resolution Melting Analysis (MS-HRMA) assay for the investigation of CST6 promoter meth...

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Detalhes bibliográficos
Main Authors: Dimitrakopoulos, Lampros, Vorkas, Panagiotis A, Georgoulias, Vasilis, Lianidou, Evi S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495665/
https://ncbi.nlm.nih.gov/pubmed/23088560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-12-486
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