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Ornithine decarboxylase mRNA is stabilized in an mTORC1-dependent manner in Ras-transformed cells
Upon ras activation, ornithine decarboxylase (ODC) is markedly induced, and numerous studies suggest that ODC expression is controlled by Ras effector pathways. ODC is therefore a potential target in the treatment and prevention of Ras-driven tumors. We compared ODC mRNA translation profiles and sta...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3495583/ https://ncbi.nlm.nih.gov/pubmed/22070140 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20111464 |
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