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NAD(P)H:Quinone oxidoreductase 1 (NQO1) protects bladder epithelium against painful bladder syndrome in mice

Painful Bladder Syndrome (PBS) or interstitial cystitis (IC) is a poorly understood chronic disease, which is characterized by thinning of bladder epithelium and intense pain. Here we demonstrate that NAD(P)H:quinone oxidoreductase 1−/− (NQO1−/−) mice developed in our laboratory represent a new anim...

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Main Authors: PATRICK, BRAD A., DAS, AMITAVA, JAISWAL, ANIL K.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495563/
https://ncbi.nlm.nih.gov/pubmed/22985937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.08.584
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