The Role of TLR and Chemokine in Wear Particle-Induced Aseptic Loosening

Wear particle-induced periprosthetic osteolysis remains the principal cause of aseptic loosening of orthopaedic implants. Monocytes/macrophages phagocytose wear particles and release cytokines that induce inflammatory response. This response promotes osteoclast differentiation and osteolysis. The pr...

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Detalles Bibliográficos
Autores principales: Gu, Qiaoli, Shi, Qin, Yang, Huilin
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2012
Materias:
Review Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495264/
https://ncbi.nlm.nih.gov/pubmed/23193363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/596870
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