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The Role of TLR and Chemokine in Wear Particle-Induced Aseptic Loosening
Wear particle-induced periprosthetic osteolysis remains the principal cause of aseptic loosening of orthopaedic implants. Monocytes/macrophages phagocytose wear particles and release cytokines that induce inflammatory response. This response promotes osteoclast differentiation and osteolysis. The pr...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Hindawi Publishing Corporation
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3495264/ https://ncbi.nlm.nih.gov/pubmed/23193363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/596870 |
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