Glut1 deficiency (G1D): Epilepsy and metabolic dysfunction in a mouse model of the most common human phenotype

Brain glucose supplies most of the carbon required for acetyl-coenzyme A (acetyl-CoA) generation (an important step for myelin synthesis) and for neurotransmitter production via further metabolism of acetyl-CoA in the tricarboxylic acid (TCA) cycle. However, it is not known whether reduced brain glu...

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Hlavní autoři: Marin-Valencia, Isaac, Good, Levi B., Ma, Qian, Duarte, Joao, Bottiglieri, Teodoro, Sinton, Christopher M., Heilig, Charles W., Pascual, Juan M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495165/
https://ncbi.nlm.nih.gov/pubmed/22683290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.04.011
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