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Computationally mapping sequence space to understand evolutionary protein engineering
Evolutionary protein engineering has been dramatically successful, producing a wide variety of new proteins with altered stability, binding affinity, and enzymatic activity. However, the success of such procedures is often unreliable, and the impact of the choice of protein, engineering goal, and ev...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3495008/ https://ncbi.nlm.nih.gov/pubmed/18020358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bp070134h |
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