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Protein structure and evolutionary history determine sequence space topology

Understanding the observed variability in the number of homologs of a gene is a very important unsolved problem that has broad implications for research into coevolution of structure and function, gene duplication, pseudogene formation, and possibly for emerging diseases. Here, we attempt to define...

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Detalhes bibliográficos
Main Authors: Shakhnovich, Boris E., Deeds, Eric, Delisi, Charles, Shakhnovich, Eugene
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC551565/
https://ncbi.nlm.nih.gov/pubmed/15741509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.3133605
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