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Protein structure and evolutionary history determine sequence space topology

Understanding the observed variability in the number of homologs of a gene is a very important unsolved problem that has broad implications for research into coevolution of structure and function, gene duplication, pseudogene formation, and possibly for emerging diseases. Here, we attempt to define...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Shakhnovich, Boris E., Deeds, Eric, Delisi, Charles, Shakhnovich, Eugene
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC551565/
https://ncbi.nlm.nih.gov/pubmed/15741509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.3133605
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