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Pacemaker Rate and Depolarization Block in Nigral Dopamine Neurons: A Somatic Sodium Channel Balancing Act
Midbrain dopamine (DA) neurons are slow intrinsic pacemakers that undergo depolarization (DP) block upon moderate stimulation. Understanding DP block is important because it has been correlated with the clinical efficacy of chronic antipsychotic drug treatment. Here we describe how voltage-gated sod...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494994/ https://ncbi.nlm.nih.gov/pubmed/23077037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1251-12.2012 |
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