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Activation of rapid oestrogen signalling in aggressive human breast cancers

Oestrogen receptors can mediate rapid activation of cytoplasmic signalling cascades by recruiting Src and PI3K. However, the involvement of this pathway in breast cancer remains poorly defined. We have previously shown that methylation of ERα is required for the formation of the ERα/Src/PI3K complex...

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Detalhes bibliográficos
Main Authors: Poulard, Coralie, Treilleux, Isabelle, Lavergne, Emilie, Bouchekioua-Bouzaghou, Katia, Goddard-Léon, Sophie, Chabaud, Sylvie, Trédan, Olivier, Corbo, Laura, Le Romancer, Muriel
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494876/
https://ncbi.nlm.nih.gov/pubmed/23065768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201201615
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