Oestrogen Non-Genomic Signalling is Activated in Tamoxifen-Resistant Breast Cancer

Endocrine therapies targeting oestrogen signalling have significantly improved breast cancer management. However, their efficacy is limited by intrinsic and acquired resistance to treatment, which remains a major challenge for oestrogen receptor α (ERα)-positive tumours. Though man...

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Detalhes bibliográficos
Main Authors: Coralie Poulard, Julien Jacquemetton, Olivier Trédan, Pascale A. Cohen, Julie Vendrell, Sandra E. Ghayad, Isabelle Treilleux, Elisabetta Marangoni, Muriel Le Romancer
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2019-06-01
Colecção:International Journal of Molecular Sciences
Assuntos:
breast cancer
resistance to endocrine therapy
oestrogen non-genomic signalling
PDX
biomarker
Acesso em linha:https://www.mdpi.com/1422-0067/20/11/2773
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