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A flagellar A-kinase anchoring protein with two amphipathic helices forms a structural scaffold in the radial spoke complex
A-kinase anchoring proteins (AKAPs) contain an amphipathic helix (AH) that binds the dimerization and docking (D/D) domain, RIIa, in cAMP-dependent protein kinase A (PKA). Many AKAPs were discovered solely based on the AH–RIIa interaction in vitro. An RIIa or a similar Dpy-30 domain is also present...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494852/ https://ncbi.nlm.nih.gov/pubmed/23148234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201111042 |
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