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A flagellar A-kinase anchoring protein with two amphipathic helices forms a structural scaffold in the radial spoke complex

A-kinase anchoring proteins (AKAPs) contain an amphipathic helix (AH) that binds the dimerization and docking (D/D) domain, RIIa, in cAMP-dependent protein kinase A (PKA). Many AKAPs were discovered solely based on the AH–RIIa interaction in vitro. An RIIa or a similar Dpy-30 domain is also present...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sivadas, Priyanka, Dienes, Jennifer M., St. Maurice, Martin, Meek, William D., Yang, Pinfen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494852/
https://ncbi.nlm.nih.gov/pubmed/23148234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201111042
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