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Myeloid Cell Specific ABCA1 Deletion Protects Mice From Bacterial Infection
RATIONALE: ATP-binding cassette transporter A1 (ABCA1) plays a critical role in eliminating excess free cholesterol (FC) from tissues by effluxing cellular FC and phospholipids to lipid-poor apolipoprotein A-I. Macrophage ABCA1 also dampens pro-inflammatory MyD88-dependent Toll-like receptor signali...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494814/ https://ncbi.nlm.nih.gov/pubmed/22955730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.269043 |
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