Myeloid Cell Specific ABCA1 Deletion Protects Mice From Bacterial Infection

RATIONALE: ATP-binding cassette transporter A1 (ABCA1) plays a critical role in eliminating excess free cholesterol (FC) from tissues by effluxing cellular FC and phospholipids to lipid-poor apolipoprotein A-I. Macrophage ABCA1 also dampens pro-inflammatory MyD88-dependent Toll-like receptor signali...

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Bibliografiske detaljer
Main Authors: Zhu, Xuewei, Westcott, Marlena M., Bi, Xin, Liu, Mingxia, Gowdy, Kymberly M., Seo, Jeongmin, Cao, Qiang, Gebre, Abraham K., Fessler, Michael B., Hiltbold, Elizabeth M., Parks, John S.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494814/
https://ncbi.nlm.nih.gov/pubmed/22955730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.269043
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