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A cell-based MHC stabilization assay for the detection of peptide binding to the canine classical class I molecule, DLA-88

Identifying immunodominant CTL epitopes is essential for studying CD8+ T-cell responses in populations, but remains difficult, as peptides within antigens typically are too numerous for all to be synthesized and screened. Instead, to facilitate discovery, in silico scanning of proteins for sequences...

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Detalhes bibliográficos
Main Authors: Ross, Peter, Holmes, Jennifer C., Gojanovich, Gregory S., Hess, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494747/
https://ncbi.nlm.nih.gov/pubmed/23062801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vetimm.2012.08.012
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