Counteracting Roles of AMP Deaminase and AMP Kinase in the Development of Fatty Liver

Fatty liver (hepatic steatosis) is associated with nucleotide turnover, loss of ATP and generation of adenosine monophosphate (AMP). It is well known that in fatty liver, activity of the AMP-activated kinase (AMPK) is reduced and that its stimulation can prevent hepatic steatosis by both enhancing f...

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Hlavní autoři: Lanaspa, Miguel A., Cicerchi, Christina, Garcia, Gabriela, Li, Nanxing, Roncal-Jimenez, Carlos A., Rivard, Christopher J., Hunter, Brandi, Andrés-Hernando, Ana, Ishimoto, Takuji, Sánchez-Lozada, Laura G., Thomas, Jeffrey, Hodges, Robert S., Mant, Colin T., Johnson, Richard J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494720/
https://ncbi.nlm.nih.gov/pubmed/23152807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048801
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