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Production of epitope-specific antibodies using peptide-CpG-ODN-liposome complex without carriers and their application as a cancer vaccine in mice

Low efficacy of peptide vaccines limits their potential application. We developed a powerful strategy to produce epitope-specific antibodies using peptides. Immunization with novel formula into mice showed target-specific prophylactic and therapeutic effects against tumors. Our strategy will be usef...

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Autori principali: Lee, YoungHee, Kwon, Hyung-Joo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494651/
https://ncbi.nlm.nih.gov/pubmed/23170285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20404
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