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ATG16L1 and pathogenesis of urinary tract infections

Autophagy is generally considered to be antipathogenic. The autophagy gene ATG16L1 has a commonly occurring mutation associated with Crohn disease (CD) and intestinal cell abnormalities. Mice hypomorphic for ATG16L1 (ATG16L1(HM)) recreate specific features of CD. Our recent study shows that the same...

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Autori principali: Wang, Caihong, Symington, Jane W., Mysorekar, Indira U.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494604/
https://ncbi.nlm.nih.gov/pubmed/22874553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.21600
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