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Endothelial cell metabolism and implications for cancer therapy
Tumour tissue is characterised by fluctuating oxygen concentrations, decreased nutrient supply, and acidic pH. The primarily glycolytic metabolism of tumour cells contributes to this, with increased glucose consumption and increased lactate secretion. Endothelial cells are particularly challenged wh...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3494441/ https://ncbi.nlm.nih.gov/pubmed/23047591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.398 |
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