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Fatty Acid-binding Protein 4, a Point of Convergence for Angiogenic and Metabolic Signaling Pathways in Endothelial Cells

Fatty acid-binding protein 4 (FABP4) is an adipogenic protein and is implicated in atherosclerosis, insulin resistance, and cancer. In endothelial cells, FABP4 is induced by VEGFA, and inhibition of FABP4 blocks most of the VEGFA effects. We investigated the DLL4-NOTCH-dependent regulation of FABP4...

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Detalhes bibliográficos
Main Authors: Harjes, Ulrike, Bridges, Esther, McIntyre, Alan, Fielding, Barbara A., Harris, Adrian L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132814/
https://ncbi.nlm.nih.gov/pubmed/24939870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.576512
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