Homeostatic adaptations in brain energy metabolism in mouse models of Huntington disease

Impairment of energy metabolism is a key feature of Huntington disease (HD). Recently, we reported longitudinal neurochemical changes in R6/2 mice measured by in-vivo proton magnetic resonance spectroscopy ((1)H MRS; Zacharoff et al, 2012). Here, we present similar (1)H MRS measurements at an early...

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Detalhes bibliográficos
Main Authors: Tkac, Ivan, Henry, Pierre-Gilles, Zacharoff, Lori, Wedel, Michael, Gong, Wuming, Deelchand, Dinesh K, Li, Tongbin, Dubinsky, Janet M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493992/
https://ncbi.nlm.nih.gov/pubmed/22805874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.104
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