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Cortical metabolites as biomarkers in the R6/2 model of Huntington's disease
To improve the ability to move from preclinical trials in mouse models of Huntington's disease (HD) to clinical trials in humans, biomarkers are needed that can track similar aspects of disease progression across species. Brain metabolites, detectable by magnetic resonance spectroscopy (MRS), h...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3293115/ https://ncbi.nlm.nih.gov/pubmed/22044866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.157 |
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