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Regulation of RhoA Signaling by the cAMP-dependent Phosphorylation of RhoGDIα
RhoA plays a pivotal role in regulating cell shape and movement. Protein kinase A (PKA) inhibits RhoA signaling and thereby induces a characteristic morphological change, cell rounding. This has been considered to result from cAMP-induced phosphorylation of RhoA at Ser-188, which induces a stable Rh...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3493914/ https://ncbi.nlm.nih.gov/pubmed/23012358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.401547 |
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