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Withdrawal of Essential Amino Acids Increases Autophagy by a Pathway Involving Ca(2+)/Calmodulin-dependent Kinase Kinase-β (CaMKK-β)

Autophagy is the main lysosomal catabolic process that becomes activated under stress conditions, such as amino acid starvation and cytosolic Ca(2+) upload. However, the molecular details on how both conditions control autophagy are still not fully understood. Here we link essential amino acid starv...

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Detalhes bibliográficos
Main Authors: Ghislat, Ghita, Patron, Maria, Rizzuto, Rosario, Knecht, Erwin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493907/
https://ncbi.nlm.nih.gov/pubmed/23027865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.365767
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