Frequency of mutations in mismatch repair genes in a population-based study of women with ovarian cancer

BACKGROUND: Mutations in genes for hereditary non-polyposis colorectal cancer (HNPCC) in ovarian cancer patients remains poorly defined. We sought to estimate the frequency and characteristics of HNPCC gene mutations in a population-based sample of women with epithelial ovarian cancer. METHODS: The...

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Detalhes bibliográficos
Main Authors: Pal, T, Akbari, M R, Sun, P, Lee, J-H, Fulp, J, Thompson, Z, Coppola, D, Nicosia, S, Sellers, T A, McLaughlin, J, Risch, H A, Rosen, B, Shaw, P, Schildkraut, J, Narod, S A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Genetics & Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493867/
https://ncbi.nlm.nih.gov/pubmed/23047549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.452
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