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Ovarian cancer risk is associated with a common variant in the promoter sequence of the mismatch repair gene MLH1

OBJECTIVES: Inherited mutations in the MLH1 gene are associated with a proportion of families with the hereditary non-polyposis colon cancer syndrome (HNPCC). The cardinal features of the syndrome are a predisposition to colon, endometrial and ovarian cancers. Recently, it has been shown that a non-...

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Detalhes bibliográficos
Main Authors: Harley, Ian, Rosen, Barry, Risch, Harvey A., Siminovitch, Kathy, Beiner, Mario E., McLaughlin, John, Sun, Ping, Narod, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3060029/
https://ncbi.nlm.nih.gov/pubmed/18405947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2007.11.046
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