Altered expression levels of IDH2 are involved in the development of colon cancer

IDH2 encodes a mitochondrial metabolic enzyme that converts isocitrate to α-ketoglutarate (α-KG) by reducing nicotinamide adenine dinucleotide phosphate (NADP(+)) to NADPH and participates in the citric acid cycle for energy production. Notably, this gene has been shown to be critical for cell proli...

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Hlavní autoři: LV, QIANG, XING, SHENYANG, LI, ZHENXIAO, LI, JIANHUA, GONG, PENGTAO, XU, XIAOFANG, CHANG, LE, JIN, XIAOXIA, GAO, FENG, LI, WEI, ZHANG, GUOCAI, YANG, JU, ZHANG, XICHEN
Médium: Artigo
Jazyk:Inglês
Vydáno: D.A. Spandidos 2012
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493704/
https://ncbi.nlm.nih.gov/pubmed/23226729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2012.676
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