Nicotinamide Adenine Dinucleotide Phosphate Oxidase (NOX) in Experimental Liver Fibrosis: GKT137831 as a Novel Potential Therapeutic Agent

BACKGROUND & AIMS: NADPH oxidase (NOX) generates reactive oxygen species (ROS) in hepatic stellate cells (HSCs) during liver fibrosis. In response to fibrogenic agonists, such as angiotensin II (Ang II), the NOX1 components form an active complex including Rac1. Superoxide dismutase 1 (SOD1) int...

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Detaylı Bibliyografya
Asıl Yazarlar: Aoyama, Tomonori, Paik, Yong-Han, Watanabe, Sumio, Laleu, Benoît, Gaggini, Francesca, Fioraso-Cartier, Laetitia, Molango, Sophie, Heitz, Freddy, Merlot, Cédric, Szyndralewiez, Cédric, Page, Patrick, Brenner, David A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493679/
https://ncbi.nlm.nih.gov/pubmed/22806357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25938
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