Endocannabinoid-Goα signalling inhibits axon regeneration in Caenorhabditis elegans by antagonizing Gqα-PKC-JNK signalling

The ability of neurons to regenerate their axons after injury is determined by a balance between cellular pathways that promote and those that inhibit regeneration. In Caenorhabditis elegans, axon regeneration is positively regulated by the c-Jun N-terminal kinase mitogen activated protein kinase pa...

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Bibliographic Details
Main Authors: Pastuhov, Strahil Iv., Fujiki, Kota, Nix, Paola, Kanao, Shuka, Bastiani, Michael, Matsumoto, Kunihiro, Hisamoto, Naoki
Format: Artigo
Language:Inglês
Published: Nature Pub. Group 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493645/
https://ncbi.nlm.nih.gov/pubmed/23072806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2136
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