Postnatal Ablation of Foxm1 from Cardiomyocytes Causes Late Onset Cardiac Hypertrophy and Fibrosis without Exacerbating Pressure Overload-Induced Cardiac Remodeling

Heart disease remains a leading cause of morbidity and mortality in the industrialized world. Hypertrophic cardiomyopathy is the most common genetic cardiovascular disorder and the most common cause of sudden cardiac death. Foxm1 transcription factor (also known as HFH-11B, Trident, Win or MPP2) pla...

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Détails bibliographiques
Auteurs principaux: Bolte, Craig, Zhang, Yufang, York, Allen, Kalin, Tanya V., Schultz, Jo El J., Molkentin, Jeffery D., Kalinichenko, Vladimir V.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493600/
https://ncbi.nlm.nih.gov/pubmed/23144938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048713
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