Tubulointerstitial De Novo Expression of the α8 Integrin Chain in a Rodent Model of Renal Fibrosis – A Potential Target for Anti-Fibrotic Therapy?

In the normal kidney, the α8 integrin chain is expressed only on mesangial cells and vascular smooth muscle cells. α8 integrin ligates several matrix molecules including fibronectin, osteopontin and fibrillin-1. Recently, we detected de novo expression of α8 integrin on epithelial cells in renal cys...

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Hlavní autoři: Hartner, Andrea, Menendez-Castro, Carlos, Cordasic, Nada, Marek, Ines, Volkert, Gudrun, Klanke, Bernd, Rascher, Wolfgang, Hilgers, Karl F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493553/
https://ncbi.nlm.nih.gov/pubmed/23144868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048362
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