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Successful treatment of murine muscular dystrophy with the proteinase inhibitor leupeptin.

Mice with genetic muscular dystrophy were treated with intraperitoneal injections of the proteinase inhibitor leupeptin, beginning before the onset of weakness. A significant number of the treated animals failed to develop histological evidence of dystrophy, compared with controls. Leupeptin treatme...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Sher, J H, Stracher, A, Shafiq, S A, Hardy-Stashin, J
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1981
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349346/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6950412/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.12.7742
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