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Successful treatment of murine muscular dystrophy with the proteinase inhibitor leupeptin.

Mice with genetic muscular dystrophy were treated with intraperitoneal injections of the proteinase inhibitor leupeptin, beginning before the onset of weakness. A significant number of the treated animals failed to develop histological evidence of dystrophy, compared with controls. Leupeptin treatme...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Sher, J H, Stracher, A, Shafiq, S A, Hardy-Stashin, J
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1981
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349346/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6950412/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.12.7742
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