Successful treatment of murine muscular dystrophy with the proteinase inhibitor leupeptin.

Mice with genetic muscular dystrophy were treated with intraperitoneal injections of the proteinase inhibitor leupeptin, beginning before the onset of weakness. A significant number of the treated animals failed to develop histological evidence of dystrophy, compared with controls. Leupeptin treatme...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sher, J H, Stracher, A, Shafiq, S A, Hardy-Stashin, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1981
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349346/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6950412/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.12.7742
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