CtIP Is Required to Initiate Replication-Dependent Interstrand Crosslink Repair

DNA interstrand crosslinks (ICLs) are toxic lesions that block the progression of replication and transcription. CtIP is a conserved DNA repair protein that facilitates DNA end resection in the double-strand break (DSB) repair pathway. Here we show that CtIP plays a critical role during initiation o...

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Detalhes bibliográficos
Main Authors: Duquette, Michelle L., Zhu, Qingyuan, Taylor, Ewan R., Tsay, Angela J., Shi, Linda Z., Berns, Michael W., McGowan, Clare H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493458/
https://ncbi.nlm.nih.gov/pubmed/23144634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003050
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