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Somatic diversification is required to generate the V kappa genes of MOPC 511 and MOPC 167 myeloma proteins.

The immune response to phosphocholine in BALB/c mice involves one group of heavy chain variable region (VH) genes and at least three groups of light chain variable region (V kappa) genes, represented by the gene products of the myelomas TEPC 15, MOPC 603, and MOPC 167/MOPC 511. The amino acid sequen...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gershenfeld, H K, Tsukamoto, A, Weissman, I L, Joho, R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349332/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6801657/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.12.7674
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