Dietary Fat Is a Lipid Source in 2,3,7,8-Tetrachlorodibenzo-ρ-Dioxin (TCDD)-Elicited Hepatic Steatosis in C57BL/6 Mice

2,3,7,8-Tetrachlorodibenzo-ρ-dioxin (TCDD) increases fatty acid (FA) transport and FA levels resulting in hepatic steatosis in mice. Diet as a source of lipids was investigated using customized diets, stearoyl-CoA desaturase 1 (Scd1) null mice, and (14)C-oleate (18:1n9) uptake studies. C57BL/6 mice...

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Detalhes bibliográficos
Main Authors: Angrish, Michelle Manente, Mets, Bryan David, Jones, Arthur Daniel, Zacharewski, Timothy Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3493189/
https://ncbi.nlm.nih.gov/pubmed/22539624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfs155
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